Job Description

The Medicinal Chemistry Scale-Up Research Scientist will work as part of the medicinal chemistry scaleup group with a high degree of independence to synthesize compounds on a range of scales from multi grams to hundreds of grams for biological evaluation. Performs experimental troubleshooting and methods development and ability to execute complex experimental procedures. Completes work in a resourceful, self-sufficient manner and is able to design alternative approaches to achieve desired outcomes. Keeps up to date with current scientific literature relevant to his/her scientific methodology or

field(s) of technical expertise. This is an onsite position at our San Diego research site.

Key Duties and Responsibilities:

• Design and undertake experimental synthetic work as part of the scale-up group to deliver material for internal customers working on 10s grams to 100s grams scale.
• Personally deliver material and independently develop and optimize processes.
• Work within the Scale-up group to enable rapid delivery of material, problem solve and share knowledge.
• Collates and interprets complex data systematically, and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities.
• Exercises solid judgment to prioritize studies, considering feasibility and Project impact.
• Performs advanced and/or complex experimental troubleshooting.
• Scours relevant scientific literature and routinely incorporates new insights into research activities.
• Identifies, prioritizes and introduces relevant emerging technologies in his/her field of expertise to advance the existing technology platforms and create/maintain a competitive advantage.
• Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals.
• Contributes significantly to patent and/or publication preparation.
• Independently prepares study presentations and presents experimental conclusions.

Required Experience / Required Knowledge/Skills

• Experience of working in a large-scale, synthetic laboratory to deliver complex organic compounds
• Display a flexible approach and be comfortable working on a variety of scales
• Experience of using large-scale glassware 5L to 20L
• Strong interpersonal skills and a team player
• Some experience and understanding of process safety and hazard assessment. A diligent approach to all safety matters.
• Very strong synthetic knowledge and mechanistic understanding

Required Education Level

• BS and 6+ years of experience
• MS and 3 years of experience, or
• PhD or post-doc with 0 - 3 years of experience in a relevant area of research, or the equivalent industrial experience

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Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com