The Johns Hopkins University is seeking a highly motivated Sr. Research Specialist who is interested to join our team to work on the in vitro and in vivo testing of brain gene therapy candidates. This candidate will participate in the development and testing of gene transfer methods for the mouse brain. They will be working on a team that includes other technicians, graduate students and postdoctoral fellows and will make significant and important contributions to various aspects of these research efforts.

This will include neuronal cultures, rodent injections, genotyping, gene expression measurement qPCR, and immunoblotting/immunohistochemistry for protein expression. Our laboratory investigates the mechanisms of synaptic plasticity and how defects in this process cause intellectual disability, autism, and epilepsy. We use a wide spectrum of techniques (molecular biology, biochemistry, cell biology, mouse genetics, histology, in vitro/in vivo imaging, omics studies) to study sensory the neurons that support learning and intelligence.

Specific Duties & Responsibilities

• Make scientific contribution to protocol development, efficiency, and productivity.
• Apply published research methods to current experimental work by investigating published protocols and discussing them with Principal Investigator (PI).
• Maintain detailed working knowledge of all assigned protocols.
• Collaborate with lab members in development of new techniques and instruments.
• Assistance with the maintenance of mouse colonies.
• Participate in the development and implementation of lab goals and objectives.
• Analyze data and process analyzed data into figures for scientific publications.
• Assist with the development and administration of laboratory budget.
• Contribute toward the efficient utilization of resources, equipment and space.
• Manage inventory, monitor supply levels, order equipment and supplies in accordance with established policies and procedures, and initiate the process for equipment repair when needed.
• Teach/train students, and new technicians in the lab. Guide, direct, and facilitate problem solving for entry-level lab members on day-to-day problems.
• Perform miscellaneous related duties as assigned.

• Bachelor's Degree in Biology, Chemistry or related field.
• Four year's experience in a comparable laboratory performing relevant techniques.
• Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.

• Prior experience with mouse experiments, biochemical techniques, histological techniques, molecular techniques and imaging.

Classified Title: Sr. Research Specialist 
Role/Level/Range: ACRP/04/MC  
Starting Salary Range: $48,000 - $84,100 Annually ($62,225 targeted; Commensurate with experience) 
Employee group: Full Time 
Schedule: M-F 8:30-5:00 
Exempt Status: Exempt 
Location: School of Medicine Campus 
Department name: ​​​​​​​SOM Neuro Sci Neuroscience  
Personnel area: School of Medicine